Cases


Ages


Table of t-tests
var1 var2 mean1 mean2 sd1 sd2 n1 n2 diff p.value
No infermary 7.192851 3.871655 5.050292 4.616596 221 41 3.321196 0.000102
No ICU 7.192851 6.610541 4.616596 5.880189 41 22 0.582311 0.657913
Infermary ICU 3.871655 6.610541 4.616596 5.880189 41 22 -2.738886 0.066494

Comorbidities


Comorbidities plot. A) 19.72% of the patients presented al least one comorbidity, with all summing for a total of 74 comorbidities; B) 14.79% of the patients presented only one comorbidity; C) 4.93% of the patients (14 patients) presented more than one comorbidity, with its comorbidity profiles being described in D).

t-test for age means per comorbidity status
var1 var2 mean1 mean2 sd1 sd2 n1 n2 diff p.value
With comorbidity Without comorbidity 6.799 6.636 5.16 5.186 56 228 0.163 0.833
Internou SemComorbidade ComComorbidade Total ComorbidadePerc
Não 202 19 221 0.086
Sim 26 37 63 0.587
# A tibble: 1 x 4
  statistic  p.value parameter method                                                      
      <dbl>    <dbl>     <int> <chr>                                                       
1      74.7 5.48e-18         1 Pearson's Chi-squared test with Yates' continuity correction

p-valor de 0.00000000000000000548 (4.48e-18), indicando forte diferença da presença de comorbidades entre hospitalizados e não hospitalizados.

Symptoms starting time


PCR


t-test for PCR means per comorbidity status
var1 var2 mean1 mean2 sd1 sd2 n1 n2 diff p.value
With comorbidity Without comorbidity 72.812 43.336 87.026 92.072 33 44 29.476 0.156

VHS


t-test for VHS means per comorbidity status
var1 var2 mean1 mean2 sd1 sd2 n1 n2 diff p.value
With comorbidity Without comorbidity 25.5 20.067 24.224 16.956 12 15 5.433 0.518

Dímero-D


t-test for Dímero-D means per comorbidity status
var1 var2 mean1 mean2 sd1 sd2 n1 n2 diff p.value
With comorbidity Without comorbidity 1467.373 477.368 2206.308 400.28 24 16 990.006 0.042

Clinical signs


Linfócitos & neutrófilos


RT-PCR, CT for SARS-CoV-2


Alvo n entre [22, 28] Percentual
N1/N 228 82 0.3596491
N2/ORF1ab 230 49 0.2130435

t-tests for N1/N
var1 var2 mean1 mean2 sd1 sd2 n1 n2 diff p.value
With comorbidity Without comorbidity 22.829 24.290 5.902 5.699 36 192 -1.461 0.177
No Infermary 24.197 23.834 5.473 7.224 185 29 0.364 0.797
No ICU 24.197 22.704 5.473 6.101 185 14 1.494 0.388
Infermary ICU 23.834 22.704 7.224 6.101 29 14 1.130 0.596
In VS Out VS 23.730 24.075 6.564 5.720 10 218 -0.345 0.874
t-tests for N2/ORF1ab
var1 var2 mean1 mean2 sd1 sd2 n1 n2 diff p.value
With comorbidity Without comorbidity 22.379 21.997 6.780 6.344 38 192 0.382 0.750
No Infermary 22.104 21.506 6.223 7.235 188 27 0.598 0.686
No ICU 22.104 22.512 6.223 7.455 188 15 -0.408 0.839
Infermary ICU 21.506 22.512 7.235 7.455 27 15 -1.006 0.675
In VS Out VS 24.080 21.959 8.144 6.311 11 219 2.121 0.414

Modelo preditivo


Output: hospitalization


Output: ICU


Output: Ventilatory support


Wrapping up